Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease.
Nitkunan, Arani; Charlton, Rebecca A; Barrick, Thomas R; McIntyre, Dominick J O; Howe, Franklyn A; and Markus, Hugh S.
2009.
Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease.
NMR in biomedicine, 22(3),
pp. 285-91.
ISSN 0952-3480
[Article]
The most consistent change in SVD is a reduction in NAA, a marker of neuronal integrity. The lack of correlation with cognition does not support the use of MRS as a surrogate disease marker.
| Item Type | Article |
|---|---|
| Subjects | Medicine and Dentistry > Clinical Medicine |
| Departments, Centres and Research Units | Psychology |
| Date Deposited | 09 Jun 2013 12:47 |
| Last Modified | 30 Jun 2017 14:11 |