Urinary incontinence following deep brain stimulation of the pedunculopontine nucleus

Aviles-Olmos, I.; Foltynie, T.; Panicker, J.; Cowie, Dorothy; Limousin, Patricia; Hariz, M.; Fowler, C. J.; and Zrinzo, L.. 2011. Urinary incontinence following deep brain stimulation of the pedunculopontine nucleus. Acta Neurochirurgica, 153(12), pp. 2357-2360. [Article]
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Low-frequency deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been reported to improve akinesia and gait difficulties in patients with
Parkinson’s disease (PD). We report on a patient with PD and L-dopa refractory gait symptoms who developed detrusor over-activity immediately after right PPN DBS. Proximity between caudal PPN and brainstem structures implicated in control of micturition is a possible explanation.

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